| USA - NCAAB | 11/21 00:00 | 1 | USC Upstate v Paine Lions | W | 79-59 | |
| USA - NCAAB | 11/18 19:00 | 1 | USC Upstate v Charleston Southern | L | 72-82 | |
| USA - NCAAB | 11/15 00:00 | 1 | USC Upstate v Georgia | L | 65-74 | |
| USA - NCAAB | 11/12 20:00 | 1 | USC Upstate v Allen | W | 85-66 | |
| USA - NCAAB | 11/11 01:00 | 1 | Minnesota v USC Upstate | L | 92-77 | |
| CIT | 03/16 23:00 | 122 | Furman v USC Upstate | L | 79-57 | |
| USA - NCAAB | 02/28 00:00 | 3 | Kennesaw St v USC Upstate | L | 80-78 | |
| USA - NCAAB | 02/24 00:00 | 1 | NJIT v USC Upstate | L | 88-87 | |
| USA - NCAAB | 02/18 19:00 | 1 |
USC Upstate
v
Florida Gulf Coast
|
L | 89-97 | |
| USA - NCAAB | 02/17 00:00 | 1 | USC Upstate v Stetson | L | 72-83 | |
| USA - NCAAB | 02/12 00:00 | 1 | North Florida v USC Upstate | W | 71-84 | |
| USA - NCAAB | 02/10 00:00 | 1 | Jacksonville v USC Upstate | W | 67-70 | |
| USA - NCAAB | 02/04 21:30 | 1 | Kennesaw State v USC Upstate | L | 84-79 | |
| USA - NCAAB | 01/31 00:00 | 1 |
USC Upstate
v
Lipscomb
|
L | 80-92 | |
| USA - NCAAB | 01/28 19:00 | 1 | USC Upstate v Kennesaw State | W | 79-73 | |
| USA - NCAAB | 01/26 00:30 | 1 |
USC Upstate
v
Lipscomb
|
L | 77-84 | |
| USA - NCAAB | 01/21 21:00 | 1 | Stetson v USC Upstate | W | 86-97 | |
| USA - NCAAB | 01/20 00:00 | 1 |
Florida Gulf Coast
v
USC Upstate
|
W | 60-62 | |
| USA - NCAAB | 01/14 19:00 | 1 | USC Upstate v Jacksonville | W | 73-66 | |
| USA - NCAAB | 01/13 00:00 | 1 | North Florida v USC Upstate | L | 73-65 | |
| USA - NCAAB | 01/07 19:00 | 1 | USC Upstate v NJIT | W | 75-65 | |
| USA - NCAAB | 01/03 00:35 | 1 | USC Upstate v UMKC | W | 84-75 | |
| USA - NCAAB | 12/30 19:00 | 1 | USC Upstate v Allen | W | 93-67 | |
| USA - NCAAB | 12/21 00:00 | 1 | USC Upstate v Florida College | W | 91-59 | |
| USA - NCAAB | 12/18 20:00 | 1 | USC Upstate v Jacksonville St | L | 66-67 | |
| USA - NCAAB | 12/16 01:00 | 1 | Alabama v USC Upstate | L | 78-61 | |
| USA - NCAAB | 12/14 00:00 | 1 | USC Upstate v Presbyterian | W | 76-48 | |
| USA - NCAAB | 12/10 19:00 | 1 | USC Upstate v Virginia's-Wise Highland Cavaliers | W | 99-67 | |
| USA - NCAAB | 12/04 18:00 | 1 | Colgate v USC Upstate | W | 65-71 | |
| USA - NCAAB | 12/03 17:00 | 1 | The Citadel v USC Upstate | L | 97-92 |
USC Upstate er et NCAA Division I basketball team baseret i Spartanburg, South Carolina. Holdet konkurrerer i Big South Conference og har vundet Big South-mesterskabet to gange, i 2009 og 2014. USC Upstate har deltaget i NCAA Tournament to gange, i 2009 og 2014. Holdet trænes af Bubba Smith.