[4] Lokomotiv Moskva 0-1 Schalke 04 [3] 2018-10-03 16:55
Stadium: RZD Arena Round: 2
Referee: Anthony Taylor Home Manager: Yury Semin Away Manager: Domenico Tedesco
Home History
| Rusland - Premier League | 2018/09/29 16:00 | Lokomotiv Moskva v FC Akhmat Grozny | W | 2-0 |
| Rusland - Pokal | 2018/09/26 18:00 | Baltika Kaliningrad v Lokomotiv Moskva | W | 2-3 |
| Rusland - Premier League | 2018/09/23 13:30 | Zenit St Petersburg v Lokomotiv Moskva | L | 5-3 |
| UEFA Champions League | 2018/09/18 19:00 | Galatasaray SK v Lokomotiv Moskva | L | 3-0 |
| Rusland - Premier League | 2018/09/14 16:30 | Lokomotiv Moskva v Dinamo Moskva | D | 1-1 |
| Rusland - Premier League | 2018/09/01 16:00 | Krasnodar v Lokomotiv Moskva | L | 2-1 |
| Rusland - Premier League | 2018/08/26 16:00 | Lokomotiv Moskva v Anzhi Makhachkala | W | 2-1 |
| Rusland - Premier League | 2018/08/19 13:30 | Krylya Sovetov v Lokomotiv Moskva | W | 0-1 |
Away History
| Tyskland - Bundesliga | 2018/09/29 13:30 | Schalke 04 v Mainz | W | 1-0 |
| Tyskland - Bundesliga | 2018/09/25 18:30 | SC Freiburg v Schalke 04 | L | 1-0 |
| Tyskland - Bundesliga | 2018/09/22 16:30 | Schalke 04 v Bayern München | L | 0-2 |
| UEFA Champions League | 2018/09/18 19:00 | Schalke 04 v FC Porto | D | 1-1 |
| Tyskland - Bundesliga | 2018/09/15 16:30 | Borussia M'gladbach v Schalke 04 | L | 2-1 |
| Tyskland - Bundesliga | 2018/09/02 16:00 | Schalke 04 v Hertha Berlin | L | 0-2 |
| Tyskland - Bundesliga | 2018/08/25 13:30 | Wolfsburg v Schalke 04 | L | 2-1 |
| Tyskland - DFB Pokal | 2018/08/17 18:45 | Schweinfurt 05 v Schalke 04 | W | 0-2 |