Stadium: Seibert Stadium Round: 1
Home Manager: Chris Hatcher Away Manager:
| NCAAF | 2021/09/18 18:30 | Samford v Western Carolina | L | 42-37 |
| NCAAF | 2021/02/27 18:00 | Western Carolina v Samford | L | 27-55 |
| NCAAF | 2019/11/16 19:00 | Samford v Western Carolina | L | 31-13 |
| NCAAF | 2018/10/06 17:30 | Western Carolina v Samford | L | 28-66 |
| NCAAF | 2017/09/23 19:30 | Western Carolina v Samford | W | 38-34 |
| NCAAF | 2022/09/17 19:30 | Presbyterian v Western Carolina | W | 21-77 |
| NCAAF | 2022/09/10 23:00 | Western Carolina v Georgia Tech | L | 17-35 |
| NCAAF | 2022/09/03 16:00 | Western Carolina v Charleston Southern | W | 52-38 |
| NCAAF | 2021/11/20 17:30 | Western Carolina v VMI | W | 52-24 |
| NCAAF | 2021/11/13 19:00 | East Tennessee State v Western Carolina | L | 56-35 |
| NCAAF | 2021/11/06 18:00 | Furman v Western Carolina | W | 42-43 |
| NCAAF | 2021/10/30 17:30 | Western Carolina v Wofford | W | 41-21 |
| NCAAF | 2021/10/23 18:00 | Western Carolina v The Citadel | W | 45-31 |
| NCAAF | 2022/09/17 23:00 | Samford v Tennessee Tech | W | 33-28 |
| NCAAF | 2022/09/10 20:00 | Samford v Georgia | L | 0-33 |
| NCAAF | 2022/09/01 23:00 | Kennesaw State v Samford | W | 17-27 |
| NCAAF | 2021/11/20 18:00 | Furman v Samford | L | 41-34 |
| NCAAF | 2021/11/13 17:00 | Samford v Florida | L | 52-70 |
| NCAAF | 2021/11/06 19:00 | The Citadel v Samford | W | 14-35 |
| NCAAF | 2021/10/30 17:30 | Samford v VMI | L | 45-46 |
| NCAAF | 2021/10/23 17:00 | Tennessee Chattanooga v Samford | L | 55-13 |