[126] Ohio 6-35 Northwestern [101] 2021-09-25 16:00
Stadium: Ryan Field Round: 1
Home Manager: Pat Fitzgerald Away Manager: Tim Albin
Home History
| NCAAF | 2021/09/17 00:00 | Ohio v Lafayette | L | 14-49 |
| NCAAF | 2021/09/11 18:00 | Duquesne v Ohio | L | 28-26 |
| NCAAF | 2021/09/04 23:00 | Syracuse v Ohio | L | 29-9 |
| NCAAF | 2020/11/28 17:00 | Bowling Green v Ohio | W | 10-52 |
| NCAAF | 2020/11/11 00:00 | Akron v Ohio | W | 10-24 |
| NCAAF | 2020/11/05 00:00 | Ohio v Central Michigan | L | 27-30 |
| NCAAF | 2020/01/03 20:30 | Ohio v Nevada | W | 30-21 |
| NCAAF | 2019/11/26 23:00 | Ohio v Akron | W | 52-3 |
Away History
| NCAAF | 2021/09/18 20:00 | Northwestern v Duke | L | 23-30 |
| NCAAF | 2021/09/11 16:00 | Indiana State v Northwestern | W | 6-24 |
| NCAAF | 2021/09/04 01:00 | Michigan State v Northwestern | L | 38-21 |
| NCAAF | 2021/01/01 18:00 | Auburn v Northwestern | W | 19-35 |
| NCAAF | 2020/12/19 17:00 | Northwestern v Ohio State | L | 10-22 |
| NCAAF | 2020/12/12 17:00 | Illinois v Northwestern | W | 10-28 |
| NCAAF | 2020/11/28 20:30 | Northwestern v Michigan State | L | 20-29 |
| NCAAF | 2020/11/21 20:30 | Wisconsin v Northwestern | W | 7-17 |