Stadium: Cancha 4 Round: 25 Ground: Clay
| ITF W25 - Buenos Aires | 2021/03/23 15:55 | Despina Papamichail v Yuki Naito | 6-1,1-6,4-6 |
| ITF W25 - Newport Beach | 2021/03/05 17:30 | Beatriz Haddad Maia v Despina Papamichail | 6-0,7-5 |
| ITF W25 - Newport Beach | 2021/03/03 22:00 | Katherine Sebov v Despina Papamichail | 4-6,7-6,3-6 |
| ITF - W25 Boca Raton | 2021/02/25 17:20 | Despina Papamichail v Gabriela Talaba | 6-4,3-6,3-6 |
| ITF - W25 Boca Raton | 2021/02/24 20:00 | Ana Sofia Sanchez v Despina Papamichail | 7-5,5-7,3-6 |
| ITF - W25 Boca Raton | 2021/02/23 18:55 | Despina Papamichail v Ana Sofia Sanchez | 6-3,6-2 |
| ITF - W25 Boca Raton | 2021/02/22 15:00 | Despina Papamichail v Barbara Gatica | 7-6,6-3 |
| ITF - W25 Orlando | 2021/02/15 15:30 | Despina Papamichail v Lucrezia Stefanini | 2-6,3-6 |
| ITF W25 - Buenos Aires | 2021/03/24 16:10 | Katharina Gerlach v Diana Marcinkevica | 6-0,6-1 |
| ITF W15 - Manacor | 2021/03/12 09:00 | Leyre Romero Gormaz v Diana Marcinkevica | 7-6,2-6,6-4 |
| ITF W15 - Manacor | 2021/03/11 10:50 | Tereza Mihalikova v Diana Marcinkevica | 2-6,2-6 |
| ITF W15 - Manacor | 2021/03/10 11:10 | Maria G Carrasco v Diana Marcinkevica | 4-6,4-6 |
| ITF W25 - Manacor | 2021/03/03 08:55 | Diana Marcinkevica v Jana Fett | 6-3,3-6,3-6 |
| ITF - W25 Poitiers | 2021/02/23 14:30 | Clara Burel v Diana Marcinkevica | 6-4,6-2 |
| ITF W25 - Altenkirchen | 2021/02/15 11:00 | Diana Marcinkevica v Susan Bandecchi | 6-3,2-6,7-10 |
| ITF W25 - Altenkirchen | 2021/02/14 16:00 | Diana Marcinkevica v Tayisiya Morderger | 6-2,6-1 |