South Carolina 35-56 Clemson 2018-11-25 00:00
Stadium: Memorial Stadium Round: 1
Home Manager: Dabo Swinney Away Manager: Will Muschamp
Head to Head
| NCAAF | 2017/11/26 00:30 | Clemson v South Carolina | L | 34-10 |
| NCAAF | 2016/11/27 00:30 | South Carolina v Clemson | L | 7-56 |
| NCAAF | 2015/11/28 17:00 | South Carolina v Clemson | L | 32-37 |
| NCAAF | 2014/11/29 17:00 | Clemson v South Carolina | L | 35-17 |
| NCAAF | 2012/11/24 12:00 | Clemson v South Carolina | W | 17-27 |
| NCAAF | 2011/11/26 12:00 | South Carolina v Clemson | W | 34-13 |
| NCAAF | 2010/11/27 12:00 | Clemson v South Carolina | W | 7-29 |
| NCAAF | 2009/11/28 12:00 | South Carolina v Clemson | W | 34-17 |
Home History
| NCAAF | 2018/11/18 00:30 | Tennessee Chattanooga v South Carolina | W | 9-49 |
| NCAAF | 2018/11/10 17:00 | South Carolina v Florida | L | 31-35 |
| NCAAF | 2018/11/03 16:00 | South Carolina v Mississippi | W | 48-44 |
| NCAAF | 2018/10/27 23:30 | Tennessee v South Carolina | W | 24-27 |
| NCAAF | 2018/10/13 19:30 | Texas A&M v South Carolina | L | 26-23 |
| NCAAF | 2018/10/06 16:00 | Missouri v South Carolina | W | 35-37 |
| NCAAF | 2018/09/29 23:30 | South Carolina v Kentucky | L | 10-24 |
| NCAAF | 2018/09/22 20:00 | South Carolina v Vanderbilt | W | 37-14 |
Away History
| NCAAF | 2018/11/18 00:00 | Duke v Clemson | W | 6-35 |
| NCAAF | 2018/11/11 01:00 | Clemson v Boston College | W | 27-7 |
| NCAAF | 2018/11/03 16:00 | Louisville v Clemson | W | 16-77 |
| NCAAF | 2018/10/27 16:00 | Clemson v Florida State | W | 59-10 |
| NCAAF | 2018/10/27 16:00 | Florida State v Clemson | W | 10-59 |
| NCAAF | 2018/10/20 19:30 | NC State v Clemson | W | 7-41 |
| NCAAF | 2018/10/06 19:30 | Clemson v Wake Forest | W | 63-3 |
| NCAAF | 2018/09/29 16:00 | Syracuse v Clemson | W | 23-27 |